Translating Time




Citation Information

If you use information from this web page, please cite the following article: 

Workman AD, Charvet CJ, Clancy B, Darlington RB, Finlay BL. 2013. Modeling transformations of neurodevelopmental sequences across mammalian species. J Neurosci. 33: 7368-7383. 

Additional References:

Original translating time model:

Finlay BL, Darlington RB. 1995. Linked regularities in the development and evolution of mammalian brains. Science. 268:1578-84.

Developmental time and brain structure

Charvet CJ, Finlay BL. 2018. Comparing adult hippocampal neurogenesis across species: translating time to predict the tempo in humans. Front Neurosci. 12.

Charvet CJ, Šimić G, Kostović I, Knezović V, Vukšić M, Leko MB, Takahashi E, Sherwood CC, Wolfe MD, Finlay BL. Coevolution in the timing of GABAergic and pyramidal neuron maturation in primates. Proc. R. Soc. B 2017 284 20171169; DOI: 10.1098/rspb.2017.1169.

Charvet CJ, Hof PR, Raghanti MA, Van Der Kouwe AJ, Sherwood CC, Takahashi E. 2017. Combining diffusion magnetic resonance tractography with stereology highlights increased cross-cortical integration in primates. J Comp Neurol. In Press.

Cahalane DJ, Charvet CJ, Finlay BL. 2014. Modeling local and cross-species neuron number variations in the cerebral cortex as arising from a common mechanism. Proc Natl Acad Sci U S A. 111:17642-7.

Charvet CJ, Cahalane DJ, Finlay BL. 2013. Systematic, Cross-Cortex Variation in Neuron Numbers in Rodents and Primates. Cereb Cortex. 25:147-60.

Dyer MA, Martins R, da Silva Filho M, Muniz JA, Silveira LC, Cepko CL, Finlay BL. 2009. Developmental sources of conservation and variation in the evolution of the primate eye. Proc Natl Acad Sci U S A. 106:8963-8. doi: 10.1073/pnas.0901484106. 

Finlay BL. 2008. The developing and evolving retina: using time to organize form. Brain Res. 1192:5-16.

Finlay BL, Silveira LCDL, Reichenbach A. 2005. Comparative aspects of visual system development. In: The structure, function and evolution of the primate visual system,  J. Kremers, ed. John Wiley and Sons pp. 37-72. 

Overview of variation and conservation in developmental timing across species

Charvet CJ, Finlay BL. 2014. Evo-devo and the primate isocortex: the central organizing role of intrinsic gradients of neurogenesis. Brain Behav Evol. 84:81-92.

Charvet CJ, Finlay BL. 2012. Embracing covariation in brain evolution: large brains, extended development, and flexible primate social systems. Prog Brain Res. 195, 71-87.

Charvet CJ, Striedter GF, Finlay BL. 2011. Evo-devo and brain scaling: candidate developmental mechanisms for variation and constancy in vertebrate brain evolution. Brain Behav Evol. 78:248-57. doi: 10.1159/000329851. 

Finlay BL, Darlington RB, Nicastro N. 2001. Developmental structure in brain evolution. Behav Brain Sci. 24:263-78; discussion 278-308.

Variation and Conservation in developmental timing within species

Charvet CJ, Darlington RB, Finlay BL. 2013. Variation in Human Brains May Facilitate Evolutionary Change toward a Limited Range of Phenotypes. Brain Behav Evol. 81:74-85.

Finlay BL, Hinz F, Darlington RB. 2011. Mapping behavioural evolution onto brain evolution: the strategic roles of conserved organization in individuals and species. Philos Trans R Soc Lond B Biol Sci. 366(1574):2111-23. doi: 10.1098/rstb.2010.0344.

Earlier model predicting event timing in humans

Clancy B, Finlay BL, Darlngton RB, Anand KJS. 2007. Extrapolating Brain Development From Experimental Species To Humans. NeuroToxicology, 28:931-937.

Clancy B, Darlington RB, Finlay BL. 2001. Translating Developmental Time Across Mammalian Species. Neuroscience 105:7-17.